Research Objectives: 

This review is divided into four sections, reflecting the three main components of human eye topography: the pupil, collarette, and iris. The fourth section focuses on inherited and acquired traits related to cardiovascular weakness in constitutional classifications. The human eye is connected to the autonomic nervous system (ANS), which controls involuntary bodily functions, through both the sympathetic and parasympathetic branches. This study investigates pupillary deformations, protrusions, collarette and iris anomalies, and their potential connections to cardiovascular pathologies, as explored by several past authors, researchers, and investigators. The balance between the sympathetic and parasympathetic systems is crucial for regulating heart rate and other physiological functions. Any disruption in this balance can lead to cardiac issues.

Full Abstract: https://www.researchgate.net/publication/387271440_Iridodiagnostics_and_Cardiovascular_Diseases_Review_Part_1_The_Pupils