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Our primary research objective was to determine if the irises reliably show signs indicating the presence of Diabetes Mellitus. We examined symptomatic patients who had already been diagnosed with the disease by common laboratory and clinical methods. In our study, we employed slitlamp-enhanced Iridology and slitlamp photography, as used successfully for many years in Russia as an adjunct to other means of diagnostic and pathology evaluation. We were able to discern certain iris patterns indicating the pre-diagnosed disease with a high degree of certainty.